Screening library
Screening libraries of polyketides to unlock therapeutic potential
Rich resource
Polyketides have evolved to interact with biological systems and to transmit biological information. They are especially useful in addressing traditionally difficult targets, such as protein-protein interactions, so they offer new approaches in diseases of high unmet need. Biotica is building a library of polyketides amenable to optimisation through novoPT™ for screening against high-content biological assays to identify polyketide leads.
Unique capabilities enable discovery approach
This approach to drug discovery offers both differentiation and exclusivity. Many companies reject natural products identified through library screening as too difficult to optimise. Biotica is uniquely able to apply its novoPT™ technology to generate novel, patentable derivatives of polyketide leads.