Publications

Find our recently published articles below.

Optimizing natural products by biosynthetic engineering: discovery of nonquinone hsp90 inhibitors (Zhang et al., 2008)25.09.2008Link
Engineered biosynthesis of hybrid macrolide polyketides containingD-angolosamine and D-mycaminose moieties (Schell et al., 2008)28.07.2008Link
Molecular characterization of macbecin as an hsp90 inhibitor. (Martin et al., 2008)22.03.2008Link
Substrate specificity of the acyl transferase domains of EpoC from the epothilone polyketide synthase (Petrovic et al., 2007)12.12.2007Link
Drug discovery beyond the ‘rule-of-five’ (Zhang & Wilkinson, 2007)26.11.2007Link
Mining and engineering natural-product biosynthetic pathways (Wilkinson & Micklefield, 2007)01.07.2007Link
Roles of rapH and rapG in Positive Regulation of Rapamycin Biosynthesis in Streptomyces hygroscopicus (Kuscer et al., 2007)27.04.2007Link
Design, synthesis and biological evaluation of ansamycin prodrugs as water-soluble Hsp90 inhibitors (AACR 2007)18.04.2007Download
Generating rapamycin analogues by directed biosynthesis: starter acid substrate specificity of mono-substituted cyclohexane carboxylic acids (Goss et al., 2006)16.10.2006Link
Separation of anti-angiogenic and cytotoxic activities of borrelidin by modification at the C17 side chain (Wilkinson et al., 2006)08.10.2006Link
Rapamycin biosynthesis: elucidation of gene product function (Gregory et al., 2006)22.08.2006Link
Biosynthesis of the angiogenesis inhibitor borrelidin: directed biosynthesis of novel analogues (Moss et al., 2006)11.05.2006Link
Biocatalysis in pharmaceutical preparation and alteration (Wilkinson & Bachmann, 2006)24.02.2006Link
Biosynthetic engineering of natural products for lead optimization and development (Wilkinson & Moss, 2005)01.11.2005Link
Mutasynthesis of rapamycin analogues through the manipulation of a gene governing starter unit biosynthesis (Gregory et al., 2005)01.07.2005Link
 
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