Publications
Find our recently published articles below.
| Preclinical characterization of novel cyclophilin inhibitors based on the polyketide, sanglifehrin (EASL 2011) | 02.04.2011 | Link |
| Biosynthesis of the immunosuppressants FK506, FK520, and rapamycin involves a previously undescribed family of enzymes acting on chorismate (Anderson et al., 2011) | 22.03.2011 | Link |
| Preclinical Characterization of Naturally Occurring Polyketide Cyclophilin Inhibitors from the Sanglifehin family (Gregory et al., 2011) | 07.03.2011 | Link |
| Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor (Qu et al., 2011) | 15.12.2010 | Link |
| A high-throughput fluorescence chemical denaturation assay as a general screen for protein–ligand binding (Mahendrarajah et al., 2011) | 05.12.2010 | Link |
| Borrelidin modulates the alternative splicing of VEGF in favour of anti-angiogenic isoforms (Woolard et al., 2011) | 23.09.2010 | Link |
| An Expeditious Route to Fluorinated Rapamycin Analogues by Utilising Mutasynthesis | 23.02.2010 | Link |
| Glycosylation engineering of spinosyn analogues containing an L-olivose moiety (Gaisser et al., 2009) | 12.03.2009 | Link |
| Optimizing natural products by biosynthetic engineering: discovery of nonquinone hsp90 inhibitors (Zhang et al., 2008) | 25.09.2008 | Link |
| Engineered biosynthesis of hybrid macrolide polyketides containingD-angolosamine and D-mycaminose moieties (Schell et al., 2008) | 28.07.2008 | Link |
| Molecular characterization of macbecin as an hsp90 inhibitor. (Martin et al., 2008) | 22.03.2008 | Link |
| Substrate specificity of the acyl transferase domains of EpoC from the epothilone polyketide synthase (Petrovic et al., 2007) | 12.12.2007 | Link |
| Drug discovery beyond the ‘rule-of-five’ (Zhang & Wilkinson, 2007) | 26.11.2007 | Link |
| Mining and engineering natural-product biosynthetic pathways (Wilkinson & Micklefield, 2007) | 01.07.2007 | Link |
| Roles of rapH and rapG in Positive Regulation of Rapamycin Biosynthesis in Streptomyces hygroscopicus (Kuscer et al., 2007) | 27.04.2007 | Link |